Two knobs are used to get a clear image on low power. The coarse adjustment knob is used to make drastic changes to the image, and the fine adjustment knob is used to make small adjustments to the image. The reason two knobs are used is because you are supposed to get as clear an image as possible on low power before moving on to the next power, and same with medium power.
The low power knob is used to get a clear image.
The coarse adjustment knob is used for achieving a clear image when focusing on low power with a microscope. It is the larger of the two focusing knobs and should be used first to bring the specimen into general focus. After that, the fine adjustment knob should be utilized for clearer, more precise focusing.
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